| Batsman | Total runs | Innings | Avg | 50s/100s | HS | SR |
| AB de Villiers (SA) | 638 (990) | 14 | 53.16 | 6/1 | 126* | 64.44 |
| A Markram (SA) | 620 (981) | 14 | 44.28 | 2/2 | 152 | 63.20 |
| D Elgar (SA) | 540 (1399) | 14 | 45.00 | 4/1 | 141* | 38.59 |
| K Mendis (SL) | 509 (867) | 7 | 72.71 | 2/2 | 196 | 58.70 |
| J Root (ENG) | 400 (852) | 9 | 50.00 | 5/0 | 83 | 46.94 |
| H Amla (SA) | 399 (957) | 14 | 28.50 | 4/0 | 82 | 41.69 |
| F du Plessis (SA) | 358 (713) | 14 | 27.53 | 2/1 | 103* | 50.21 |
| D Chandimal (SL) | 346 (742) | 7 | 57.66 | 1/1 | 119* | 46.63 |
| U Khawaja (AUS) | 336 (690) | 9 | 37.33 | 2/1 | 171 | 48.69 |
| M Haque (BAN) | 314 (438) | 4 | 78.50 | 0/2 | 176 | 71.68 |
| R Silva (SL) | 308 (671) | 7 | 51.33 | 2/1 | 109 | 45.90 |
| S Marsh (AUS) | 303 (701) | 9 | 33.66 | 0/1 | 156 | 43.22 |
| Q de Kock (SA) | 294 (466) | 13 | 22.61 | 2/0 | 83 | 63.09 |
| V Kohli (IND) | 286 (475) | 6 | 47.66 | 1/1 | 153 | 60.21 |
| M Marsh (AUS) | 277 (517) | 9 | 30.77 | 1/1 | 101 | 53.57 |
| D Warner (AUS) | 273 (420) | 7 | 39.00 | 3/0 | 63 | 65.00 |
Last update: 18 Jun 2018
Glossary: Avg-Average, HS-Highest score, SR-Strike rate
Check out: Leading run-scorers in Twenty20 cricket, Tests this year