| Batsman | Runs | Inns | Avg | 50s/100s | HS | SR |
| M Rizwan (Pak) | 1326 (983) | 26 | 73.66 | 12/1 | 104* | 134.89 |
| Babar Azam (Pak) | 939 (736) | 26 | 37.56 | 9/1 | 122 | 127.58 |
| M Guptill (NZ) | 678 (466) | 18 | 37.66 | 5/0 | 97 | 145.49 |
| M Marsh (Aus) | 627 (483) | 20 | 36.88 | 6/0 | 77* | 129.81 |
| J Buttler (Eng) | 589 (411) | 14 | 65.44 | 5/1 | 101* | 143.30 |
| M Naim (Ban) | 575 (573) | 26 | 23.00 | 3/0 | 64 | 100.34 |
| A Markram (SA) | 570 (383) | 16 | 43.84 | 6/0 | 70 | 148.82 |
| Q de Kock (SA) | 524 (399) | 14 | 43.66 | 5/0 | 72 | 131.32 |
| Mahmudullah (Ban) | 496 (471) | 26 | 23.61 | 2/0 | 52 | 105.30 |
| Evin Lewis (WI) | 489 (314) | 18 | 28.76 | 4/0 | 79 | 155.73 |
| N Pooran (WI) | 484 (371) | 21 | 25.47 | 2/0 | 64 | 130.45 |
| S Ssesazi (Uganda) | 483 (431) | 16 | 34.50 | 4/0 | 63 | 112.06 |
| P Stirling (Ire) | 482 (384) | 16 | 34.42 | 1/1 | 115* | 125.52 |
| A Finch (Aus) | 459 (367) | 17 | 28.68 | 3/0 | 79* | 125.06 |
| Saud Islam (Uganda) | 452 (426) | 19 | 26.58 | 3/0 | 75 | 106.10 |
| R Berrington (Sco) | 447 (355) | 13 | 49.66 | 4/0 | 82* | 125.91 |
| D Conway (NZ) | 428 (317) | 13 | 47.55 | 2/0 | 99* | 135.01 |
| Jason Roy (Eng) | 426 (290) | 15 | 30.42 | 2/0 | 64 | 146.89 |
| R Sharma (Ind) | 424 (281) | 11 | 38.54 | 5/0 | 74 | 150.88 |
| Thamotharam (Malta) |
419 (299) | 18 | 26.18 | 1/1 | 104* | 140.13 |
| F Zaman (Pak) | 415 (326) | 20 | 24.41 | 3/0 | 60 | 127.30 |
| H Lakov (Bulgaria) |
414 (374) | 12 | 51.75 | 5/0 | 80 | 110.69 |
| R Hendricks (SA) | 413 (327) | 15 | 29.50 | 3/0 | 69 | 126.29 |
| B Arora (Malta) |
406 (442) | 17 | 31.23 | 2/0 | 66* | 91.85 |
| S Adedeji (Nigeria) |
403 (439) | 18 | 25.18 | 2/0 | 68 | 91.79 |
| Van der Dussen (SA) | 391 (316) | 14 | 39.10 | 3/0 | 94* | 123.73 |
| Afif Hossain (Ban) | 390 (335) | 25 | 18.57 | 0/0 | 49* | 116.41 |
| D Malan (Eng) | 384 (331) | 16 | 27.42 | 2/0 | 76 | 116.01 |
| C Williams (Nam) | 378 (323) | 14 | 27.00 | 4/0 | 81 | 117.02 |
| D Miller (SA) | 377 (252) | 15 | 47.12 | 2/0 | 85* | 149.60 |
| Ronak Patel (Uganda) | 357 (320) | 16 | 32.45 | 2/0 | 68* | 111.56 |
| Ronak Patel (Uganda) | 357 (320) | 16 | 32.45 | 2/0 | 68* | 111.56 |
| Louis Bruce (Gibraltar) |
356 (285) | 9 | 44.50 | 5/0 | 73 | 124.91 |
| Riazat Ali (Uganda) | 350 (250) | 16 | 26.92 | 1/0 | 59 | 140.00 |
| Alex Obanda (Kenya) | 343 (228) | 11 | 38.11 | 0/1 | 103* | 150.43 |
| W Madhevere (Zim) | 341 (286) | 16 | 21.31 | 3/0 | 73 | 119.23 |
| L Simmons (WI) | 338 (298) | 14 | 26.00 | 1/0 | 72 | 113.42 |
| R Satheesan (Romania) |
330 (164) | 9 | 41.25 | 3/0 | 76 | 201.21 |
| Shakib (Ban) | 327 (306) | 17 | 19.23 | 0/0 | 46 | 106.86 |
| T Barker (Luxembourg) |
325 (255) | 8 | 40.62 | 2/0 | 78 | 127.45 |
| G Phillips (NZ) | 321 (224) | 16 | 26.75 | 1/0 | 58* | 143.30 |
| Rayyan Pathan (Canada) |
312 (190) | 6 | 78.00 | 2/1 | 107* | 164.21 |
| Ishan De Silva (Bulgaria) |
304 (269) | 12 | 27.63 | 1/1 | 100* | 113.01 |
| Ivan Selemani (Tanzania) |
302 (183) | 10 | 33.55 | 2/0 | 81 | 165.02 |
| M Wade (Aus) | 302 (231) | 18 | 18.87 | 0/0 | 44 | 130.73 |
| P Nissanka (SL) | 302 (258) | 11 | 27.45 | 3/0 | 72 | 117.05 |
| Kevin O’Brien (Ire) | 301 (277) | 14 | 21.50 | 2/0 | 60 | 108.66 |
| V Kohli (Ind) | 299 (225) | 8 | 74.75 | 4/0 | 80* | 132.88 |
| K Williamson (NZ) | 298 (254) | 12 | 29.80 | 2/0 | 85 | 117.32 |
| Dinesh Nakrani (Uganda) | 295 (211) | 18 | 29.50 | 1/0 | 67 | 139.81 |
| M O’Dowd (Ned) | 295 (217) | 7 | 49.16 | 2/1 | 133* | 135.94 |
| C Asalanka (SL) | 295 (222) | 9 | 36.87 | 2/0 | 80* | 132.88 |
| D Warner (Aus) | 289 (197) | 7 | 48.16 | 3/0 | 89* | 146.70 |
| D Mitchell (NZ) | 289 (205) | 12 | 28.90 | 1/0 | 72* | 140.97 |
| KL Rahul (Ind) | 289 (221) | 11 | 28.90 | 4/0 | 69 | 130.76 |
| S Hetmyer (WI) | 287 (237) | 12 | 26.09 | 2/0 | 81* | 121.09 |
| G Munsey (Sco) | 283 (228) | 13 | 21.76 | 2/0 | 54 | 124.12 |
| Irfan Karim (Kenya) | 280 (264) | 12 | 31.11 | 3/0 | 67 | 106.06 |
| K Bhurtel (Nep) | 278 (198) | 5 | 69.50 | 4/0 | 77 | 140.40 |
| Taranjeet (Romania) |
276 (141) | 8 | 39.42 | 3/0 | 91 | 195.74 |
| Azhar Andani (Portugal) |
276 (179) | 4 | 69.00 | 1/1 | 100 | 154.18 |
| C Ervine (Zim) | 275 (238) | 9 | 34.37 | 1/0 | 67* | 115.54 |
| C Gayle (WI) | 272 (242) | 21 | 15.11 | 1/0 | 67 | 112.39 |
| G Erasmus (Nam) | 266 (222) | 14 | 24.18 | 2/0 | 62* | 119.81 |
| Z Kukikhel (Hungary) |
263 (150) | 4 | 65.75 | 3/0 | 82 | 175.33 |
| R Burl (Zim) | 262 (211) | 14 | 32.75 | 0/0 | 40 | 124.17 |
| J Bairstow (Eng) | 258 (208) | 17 | 21.50 | 1/0 | 51 | 124.03 |
| K Nassoro (Tanzania) |
254 (186) | 10 | 50.80 | 1/0 | 59* | 136.55 |
| T Bavuma (SA) | 252 (220) | 12 | 22.90 | 1/0 | 72 | 114.54 |
| N Dhaliwal (Canada) |
251 (164) | 6 | 50.20 | 2/0 | 69* | 153.04 |
| R Chakabva (Zim) | 251 (181) | 14 | 17.92 | 0/0 | 48 | 138.67 |
| S Sarkar (Ban) | 251 (224) | 16 | 15.68 | 3/0 | 68 | 112.05 |
Related: Leading runs in Test this year
Glossary: Avg-Average, HS-Highest score, Inns-Innings, SR-Strike rate; Aus-Australia, Ban-Bangladesh, Eng-England, Ind-India, NZ-New Zealand, Pak-Pakistan, SA-South Africa, SL-Sri Lanka, WI-West Indies, Zim-Zimbabwe