| Batsman | Sixes | Innings |
| Asif Ali (IU) | 26 | 11 |
| K Pollard (PZ) | 23 | 13 |
| S Watson (QG) | 22 | 12 |
| K Akmal (PZ) | 18 | 13 |
| L Ronchi (IU) | 17 | 12 |
| U Akmal (QG) | 16 | 10 |
| C Ingram (KK) | 16 | 11 |
| L Livingstone (KK) | 15 | 11 |
| C Delport (IU) | 13 | 12 |
| Sohail Akhtar (LQ) | 12 | 9 |
| D Sammy (PZ) | 11 | 10 |
| F Zaman (LQ) | 10 | 10 |
| D Wiese (LQ) | 10 | 6 |
| James Vince (MS) | 10 | 8 |
| Shoaib Malik (MS) | 9 | 9 |
| Imam-ul-Haq (PZ) | 8 | 12 |
| Umar Siddiq (MS) | 8 | 7 |
| C Walton (IU) | 8 | 4 |
| Faheem Ashraf (IU) | 8 | 10 |
| A Shehzad (QG) | 8 | 8 |
| Ahsan Ali (QG) | 7 | 8 |
| Liam Dawson (PZ) | 6 | 8 |
| Dan Christian (MS) | 5 | 7 |
| AB de Villiers (LQ) | 5 | 7 |
| H Talat (IU) | 5 | 9 |
| J Charles (MS) | 5 | 6 |
| Misbah-ul-Haq (PZ) | 5 | 3 |
| R Rossouw (QG) | 5 | 12 |
| C Munro (KK) | 4 | 8 |
| A Fletcher (PZ) | 4 | 4 |
| Anwar Ali (QG) | 4 | 3 |
| Iftikhar Ahmed (KK) |
4 | 6 |
| Ben Dunk (KK) | 4 | 7 |
| A Russell (MS) | 3 | 4 |
| Sohaib Maqsood (PZ) |
3 | 5 |
| Umar Amin (PZ) | 3 | 8 |
| C Anderson (LQ) | 3 | 2 |
| Sarfaraz Ahmed (QG) |
2 | 7 |
| Wahab Riaz (PZ) | 2 | 8 |
| Shahid Afridi (MS) | 2 | 7 |
| Imad Wasim (KK) | 2 | 10 |
| Aamer Yamin (KK) | 2 | 4 |
| M Nawaz (QG) | 2 | 6 |
| Babar Azam (KK) | 2 | 11 |
| Haris Sohail (LQ) | 1 | 5 |
| M Amir (KK) | 1 | 5 |
| A Devcich (LQ) | 1 | 5 |
| Haris Rauf (LQ) | 1 | 3 |
| Shan Masood (MS) | 1 | 4 |
| R Wessels (LQ) | 1 | 2 |
| Z Gohar (IU) | 1 | 2 |
| D Gunaratne (LQ) | 1 | 1 |
| A Hales (IU) | 1 | 2 |
| Shadab Khan (IU) | 1 | 9 |
| Samit Patel (IU) | 1 | 6 |
| W Parnell (IU) | 1 | 2 |
| M Rizwan (KK) | 1 | 5 |
| M Hafeez (LQ) | 1 | 2 |
| Gauhar Ali (LQ) | 1 | 3 |
| B Taylor (LQ) | 1 | 4 |
| Hammad Azam (MS) | 1 | 5 |
| Yasir Shah (LQ) | 1 | 2 |
Related: Who’s leading the run charts?
Glossary: Avg-Average, HS-Highest score, Inns-Innings, SR-Strike rate; IU-Islamabad United, KK-Karachi Kings, LQ-Lahore Qalandars, MS-Multan Sultans, PZ-Peshawar Zalmi, QG-Quetta Gladiators