| Bowler | Wickets | Inns | Avg | Overs | BBI | SR |
| A Nagwaswalla (Gujarat) |
19 | 6 | 12.00 | 53.2 | 6/54 | 16.8 |
| Shivam Sharma (Uttar Pradesh) |
18 | 5 | 11.88 | 47.1 | 7/31 | 15.7 |
| R Dhawan (Himachal) |
16 | 4 | 13.25 | 38.5 | 6/27 | 14.5 |
| S Kaul (Punjab) |
14 | 5 | 18.57 | 47.1 | 4/27 | 20.2 |
| D Kulkarni (Mumbai) |
13 | 4 | 8.69 | 31.2 | 5/44 | 14.4 |
| S Sreesanth (Kerala) |
13 | 6 | 24.38 | 54.4 | 5/65 | 25.2 |
| S Bachhav (Maharashtra) |
12 | 5 | 22.25 | 50 | 3/59 | 25.0 |
| S Gopal (Karnataka) |
12 | 6 | 22.83 | 52.2 | 3/41 | 26.1 |
| Ravi Teja (Hyderabad) |
12 | 5 | 24.91 | 46 | 4/45 | 23.0 |
| P Solanki (Mumbai) |
11 | 3 | 13.72 | 25 | 5/48 | 13.6 |
Glossary: Avg-Average, BBI-Best bowling innings, Inns-Innings, SR-Strike rate
Related: VHT 2021 batting record