| Bowler | Wickets | Inns | Avg | Overs | BBI | SR |
| Shivam Sharma (Uttar Pradesh) |
21 | 8 | 16.90 | 77.1 | 7/31 | 22.0 |
| A Nagwaswalla (Gujarat) |
19 | 7 | 13.94 | 61.2 | 6/54 | 19.3 |
| R Dhawan (Himachal) |
16 | 4 | 13.25 | 38.5 | 6/27 | 14.5 |
| P Solanki (Mumbai) |
15 | 6 | 21.46 | 52 | 5/48 | 20.8 |
| D Kulkarni (Mumbai) |
14 | 6 | 11.78 | 44.2 | 5/44 | 19.0 |
| S Kaul (Punjab) |
14 | 5 | 18.57 | 47.1 | 4/27 | 20.2 |
| Prasidh Krishna (Karnataka) |
14 | 7 | 22.21 | 57.1 | 4/17 | 24.5 |
| S Sreesanth (Kerala) |
13 | 6 | 24.38 | 54.4 | 5/65 | 25.2 |
| P Sangwan (Delhi) |
13 | 7 | 25.46 | 55.3 | 3/59 | 25.6 |
| S Gopal (Karnataka) |
13 | 7 | 27.38 | 62.2 | 3/41 | 28.7 |
Glossary: Avg-Average, BBI-Best bowling innings, Inns-Innings, SR-Strike rate
Related: VHT 2021 batting record